Cerebellum

  • 15% volume

  • 69 billion neurons (most of the neurons!)

    • Cerebrum (16B) + Cerebellum (69B) = 99% of total # neurons
  • Cerebellar hypoplasia

    • Small cerebellum → abnormal motility
    • ⇒ cerebellum — movement?
  • Cerebellum-deficit mouse

    ⇒ Coordination impairment of walking legs

  • King et al. Nature Neurosci, 2019

    • Diverse functions are mapped into a cerebellum
  • ⇒ Cerebellum may be highly related to high-level cognitive functions

    • Autism — cerebellum (almost tobacco — lung cancer)
      • Autism patients often show movement problems